antiphospholipid syndrome presenting with superior vena cava thrombosis
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Superior Vena Cava Thrombosis
Superior vena cava syndrome (SVCS) is characterized by gradual, insidious compression or obstruction of the superior vena cava (SVC). The most common etiology of SVCS is related to malignancy such as bronchogenic CA and lymphoma. Other cases have a variety of causes such as chronic infections and chronic inflammations that involve the mediastinum. Spontaneous SVC thrombosis is also known to occ...
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Approximately 15,000 cases of superior vena cava (SVC) obstruction are diagnosed in the United States annually. Malignancies (primarily lung cancer) are the underlying cause of 80-85% of cases, leaving 15-20% caused by various benign conditions, including sclerosing mediastinitis (the diagnosis in our case). Thrombolytic therapy and major advances in vascular techniques in recent years have imp...
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Superior vena cava (SVC) syndrome is not an uncommon occurrence in patients with malignancy and it is often described as a medical emergency. In majority of the cases, SVC syndrome occurs due to mechanical obstruction of the SVC by extraluminal compression with primary intrathoracic malignancies. However, intraluminal obstruction due to thrombosis can also produce symptoms and signs of SVC synd...
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Journal title:
iranian journal of immunologyجلد ۶، شماره ۲، صفحات ۱۰۳-۱۰۶
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